semanticsSBML 2.0 - A Collection of Online Services for SBML Models

SBML (Systems Biology Markup Language) models of biochemical network models are a fast, efficient, and widely spread effort in analyzing pathways and networks. Vast amounts of software tools provide the handling of SBML files. semanticSBML 2.0 is an advanced, improved, and extended version of the systems biology tool semanticSBML. While the latter had to be downloaded, installed and furthermore was limited in capabilities, the newly introduced and browser-enabled systems biology platform semanticSBML 2.0 can be accessed online from every operating system. It is a collection of numerous online services for the processing of SBML (Systems Biology Markup Language) files. It does not only comprise of the former semanticSBML features, but also offers many new tools for the annotation, merging, building, checking, and visualization of SBML models. The processing of SBML models is based on the model elements and their semantic annotations. These annotations are identifiers of specific syntax linking the model elements to different web resources holding immense biochemical information (for instance KEGG, ChEBI, SBO). Our internal database libSBAnnotation is the annotational foundation of our SBML tools and holds identifiers from numerous web resources, also including cross-links among them.